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This Author: Vincent Racaniello

This Week in Microbiology Podcast by Vincent Racaniello

This Week in Microbiology Podcast

by Vincent Racaniello

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Description

This Week in Microbiology is a podcast about unseen life on Earth hosted by Vincent Racaniello and friends. Following in the path of his successful shows 'This Week in Virology' (TWiV) and 'This Week in Parasitism' (TWiP), Racaniello and guests produce an informal yet informative conversation about microbes which is accessible to everyone, no matter what their science background.


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 Podcast Website:
http://www.microbeworld.org/twim

TWiM #150: Microbiology is where it’s at


Thu, Apr 20, 2017


In recognition of National Medical Laboratory Professionals Week, Robin Patel speaks with the TWiM team about directing a clinical bacteriology laboratory, and how an observation made by a laboratory technologist lead to the finding that Ureaplasma species can cause a system metabolic disturbance, hyperammonemia.

Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson

Guest: Robin Patel

Links for this episode:

Become a patron of TWiM.

 



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TWiM #149: You’re going to learn R


Thu, Apr 06, 2017


The TWiM team speaks with Pat Schloss about assigning sequence data to operational taxonomic units, and his experience with mSphere Direct, a new way of submitting papers for publication.

Hosts: 

Vincent Racaniello, Michael SchmidtElio Schaechter, and Michele Swanson.

Special guest: Pat Schloss

Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Become a patron of TWiM.

Links for this episode

This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free – WITH FREE SHIPPING – by going to blueapron.com/twim

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv



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TWiM #148: Neanderthal Dentistry


Thu, Mar 23, 2017


Vincent, Elio, and Michael reveal what Neanderthals ate from analysis of DNA in their teeth, and new CRISPR-Cas systems found in the genomes of uncultured microbes.

Hosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt.

Subscribe to TWiM (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Become a patron of TWiM.

Links for this episode

This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free – WITH FREE SHIPPING – by going to blueapron.com/twim

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv 



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TWiM #147: The Public Goods Dilemma


Fri, Mar 10, 2017


The TWiM hosts reveal why phosphorus is essential for fungal brain disease, and how bacteria kill local competitors to favor the evolution of public goods cooperation.

Hosts: 

Vincent Racaniello, Michele Swanson, Michael Schmidt, and Elio Schaechter.

Links for this episode

Become a patron of TWiM.

This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free with your first purchase – WITH FREE SHIPPING – by going to blueapron.com/twim

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 



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TWiM #146: Viral arbitrium


Thu, Feb 23, 2017


Vincent, Elio and Michael discuss the finding of a prion in bacteria, and how communication between bacteria guides the decision between lysis and lysogeny.

Hosts: 

Vincent Racaniello, Michael Schmidt, and Elio Schaechter.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Become a patron of TWiM.

Links for this episode

This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free – WITH FREE SHIPPING – by going to blueapron.com/twim

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 



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TWiM Special: Q fever with Robert Heinzen


Thu, Feb 16, 2017


Host: Vincent Racaniello

Guest: Robert Heinzen

At the Rocky Mountain Laboratory in Hamilton, Montana, Vincent speaks with Robert Heinzen about the work of his laboratory on Q fever and its causative microbe, Coxiella burneti.

 

Become a Patron of TWiM!

Links for this episode

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv



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TWiM #145: Anything but academic


Thu, Feb 09, 2017


Vincent meets up with Catharine Bosio, Michael Merchlinsky, and Shilpa Gadwal at the ASM Biothreats meeting to talk about careers for scientists outside of the ivory tower.

Become a patron of TWiM.

Links for this episode:

 



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TWiM #144: Did eukaryotes invent anything?


Thu, Jan 26, 2017


The TWiMers discuss how changes in domestic laundering affect the removal of microorganisms, and assembly of a nucleus-like structure during viral replication in bacteria.

Hosts: 

Vincent Racaniello, Michael SchmidtElio Schaechter, and Michele Swanson.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Become a patron of TWiM.

Links for this episode

This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free – WITH FREE SHIPPING – by going to blueapron.com/twim

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 



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TWiM #143: E-scaffolds and receptor transfer


Thu, Jan 12, 2017


Vincent, Michael, and Michele explain the use of an electrochemical gradient to eliminate bacterial biofilms, and how phage susceptibility can be transferred by exchange of receptor proteins.

Hosts: 

Vincent Racaniello, Michael Schmidt, and Michele Swanson.

Right click to download TWiM#143 (32 MB .mp3, 66 minutes).

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Become a patron of TWiM.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv 



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TWiM #142: A membrane-thickness caliper


Thu, Dec 29, 2016


Vincent, Elio and Michele wind up a year of microbial podcasts with a story about the lack of resistance to a crop antifungal compound, and how a bacterium uses a molecular caliper to measure membrane thickness.

Hosts: 

Vincent Racaniello, Elio Schaechter, and Michele Swanson.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv 



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TWiM #141: Nutritional immunity and polymicrobial infections


Thu, Dec 15, 2016


Jennifer joins Vincent, Elio, and Michael to talk about the work of her laboratory on how a respiratory virus enhances bacterial growth by dysregulating nutritional immunity.

Hosts: 

Vincent Racaniello, Elio Schaechter, and Michael Schmidt.

Guest: Jennifer Bomberger

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

This show is sponsored by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. This Holiday season give someone a Drobo to keep all their files and memories safe forever

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 



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TWiM 140: Small town, big science


Thu, Dec 01, 2016


Host: Vincent Racaniello

Guests: Marie Antonioli, Bryan Hansen, Forrest Jessop, Kyle Shifflet and Jim Striebel

At the Hamilton, Montana Performing Arts Center, Vincent speaks with three local high school graduates and two high school teachers about how Rocky Mountain Laboratories influenced school science programs and opened up career opportunities.

 

Subscribe to TWiM (free) on iTunesStitcherAndroidRSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Become a Patron of TWiM!

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv



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TWiM #139: Frackibacter and sticky fingers


Fri, Nov 18, 2016


The TWiM team discusses microbial DNA found on ATM machines in New York City, and how hydraulic fracturing, or fracking, alters microbial ecosystems deep in the Earth.

Hosts: 

Vincent Racaniello, Michael SchmidtElio Schaechter, and Michele Swanson.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Register today for the 2017 ASM Scientific Writing and Publishing Online Course at bit.ly/swpoc17

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 



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TWiM #138: Learning to love uranium and the A-baum


Thu, Nov 03, 2016


The TWiM team brings you a bacterium from a Colorado field site that grows on uranium, and copper resistance in the emerging pathogen Acinetobacter baumannii.

Hosts: 

Vincent Racaniello, Michael SchmidtElio Schaechter, and Michele Swanson.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m?icrobe ?and use the promo code MICROBE?.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 



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TWiM #137: The battle for oxygen


Thu, Oct 20, 2016


Highlights of the Recent Advances in Microbial Control meeting in San Diego, and expansion of a gut pathogen by virulence factors that stimulate aerobic respiration.

Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m?icrobe ?and use the promo code MICROBE?.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 



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TWiM #136: Diderms and then monoderms


Fri, Oct 07, 2016


Them TWiM team discusses the importance of neutrophils in microbial infections, and evidence that ancient bacteria had two cell walls.

Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m?icrobe ?and use the promo code MICROBE?.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 



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TWiM #135: Unruly individuals and their unruly friends


Fri, Sep 23, 2016


Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m?icrobe ?and use the promo code MICROBE?.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 



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TWiM #134: Lipids that live forever


Thu, Sep 08, 2016


Design of a synchronously lysing bacterium for delivery of anti-tumor molecules in mice, and hopanoids, the lipids that live forever, brought to you by the four Microbies of TWiM.

Hosts: Vincent Racaniello, Elio Schaechter, Michael Schmidt, and Michele Swanson.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m?icrobe ?and use the promo code MICROBE?.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 



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TWiM #133: Right under our noses


Sat, Aug 20, 2016


Insight into the biology of rhinovirus C from cryo-electron microscopy, and a novel antibiotic from a commensal bacterium that grows in the human nose, from the doctors of TWiM.

Hosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

Image in audio player: Molecular surface of a Human rhinovirus, showing protein spikes. By: Wiki user: Robin S

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m?icrobe ?and use the promo code MICROBE?.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 



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TWiM #132: Bacteria learn long division


Fri, Aug 05, 2016


Vincent, Elio, and Michele present cell division by longitudinal scission in an insect symbiont, and thermally activated charge transport in microbial nanowires.

Hosts: Vincent RacanielloMichele Swanson and Elio Schaechter.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m?icrobe ?and use the promo code MICROBE?.

This episode is also brought to you by Drobo, a family of safe, expandable, yet simple to use storage arrays. Drobos are designed to protect your important data forever. Visit www.drobo.com to learn more. Listeners can save $100 on a Drobo system at drobostore.com by using the discount code Microbe100.

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 



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TWiM 131: Mice behaving badly


Wed, Jul 20, 2016


Hosts: Vincent Racaniello and Michael Schmidt

Michael and Vincent present Spotlights, brief reviews of classic papers in the Journal of Bacteriology, and explain how a single bacterial species can reverse autism-like social deficits in the offspring of obese mice.

 

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/microbe and use the promo code MICROBE.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv



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TWiM #130: Interkingdom interactions at ASM Microbe


Thu, Jun 23, 2016


Filmed live in Boston, MA at Microbe 2016, David S. Schneider and Vanessa Sperandio talk about their work on regulation of bacterial virulence in the gut by bacterial adrenergic sensors, and the physiological mechanisms that make us ill and that help us recover.



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TWiM #129: Dried and wrinkled, smooth and mucoid


Tue, Jun 07, 2016


The arrival in the US of plasmid-mediated resistance to colistin antibiotics, a last line of defense against many gram-negative bacilli, and a quorum sensing system in a eukaryote are topics of this episode hosted by Vincent, Michael, and Michele.

Image: Etest used to determine the minimum inhibitory concentration of an antibiotic for a particular bacterium.

Hosts: Vincent RacanielloMichael Schmidt, and Michele Swanson. 

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completely free if you sign up at curiositystream.com/m?icrobe ?and use the promo code MICROBE?.

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 



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TWiM #128: A moonlighting phage protein


Sat, May 21, 2016


A eukaryote without a mitochondrion, and using a phage enzyme to eliminate intracellular bacteria are two topics discussed by the TWiMers on this episode.

Image (right): An entry in the ASM Agar Art Contest which bears an uncanny resemblance to one of the TWiM hosts.TWiV agar art

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is brought to you by CuriosityStream, a subscription streaming service that offers over 1,400 documentaries and non­fiction series from the world's best filmmakers. Get unlimited access starting at just $2.99 a month, and for our audience, the first two months are completel free if you sign up at curiositystream.com/m?icrobe ?and use the promo code MICROBE?.

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 



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TWiM #127: Subway Snowblowers and Men in Black


Thu, May 05, 2016


The TWiM team explores microbes in snowblower vents on the ocean floor, and cleavage of antibody molecules by a Mycoplasma protease.

Image (right): Photograph of the ‘Subway’ snowblower vent on the sea floor at Axial Seamount, Juan de Fuca Ridge. Visible are white ‘snow’ in the vent and orange floc on the seafloor. Credit: Canadian Scientific Submersible Facility and the University of Washington

Hosts: Vincent Racaniello, Elio Schaechter, Michele Swanson, and Michael Schmidt.

snowblower vent800

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Agar Art Contest and ASM Grant Writing Course

Send your microbiology questions and comments (email or mp3 file) to twim@microbe.tv 



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TWiM #126: I’m not scared of zebrafish and mice and bears (oh my!)


Fri, Apr 22, 2016


The microbiome of hibernating bears, and zebrafish as a model for bacterial sepsis feature in this animal-centric episode of TWiM hosted by Vincent, Michael, and Michele.

Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Agar Art Contest and ASM Microbe 2016

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

 



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TWiM #125: A minimal cell operating system


Thu, Apr 07, 2016


Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt.

A deep sequencing study of commercially available probiotics, and design and synthesis of a minimal bacterial genome are the topics tackled by Vincent, Michael, and Michele on this episode of TWiM.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

This episode is sponsored by ASM Agar Art Contest and ASM Microbe 2016

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

 

 



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TWiM #124: Fungal pirates


Thu, Mar 24, 2016


Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt.

Vincent, Michael, and Michele reveal how a fungal protease blunts the innate immune response and promotes pathogenicity.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

 

This episode is sponsored by ASM Agar Art Contest and ASM Microbe 2016

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.



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TWiM #123: A microbial MAGE


Wed, Mar 09, 2016


Hosts: Vincent RacanielloMichael Schmidt, and Elio Schaechter.

Guest: Harris Wang

Harris joins Vincent, Elio, and Michael to describe multiplex automated genome engineering, a method for targeting many modifications in a population of bacterial cells.

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode 

This episode is sponsored by Microbe Magazine Podcast and ASM Microbe 2016

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv.

 



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TWiM #122: Mayonii, microRNAs and the microbiome


Thu, Feb 25, 2016


Vincent, Michele, and Michael reveal the discovery of a new species of the spirochaete that causes Lyme disease, and fecal microRNAs that shape the gut microbiome.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

Identification of a novel Borrelia species causing Lyme disease (Lancet Inf Dis)

Parasite wonders with Bobbi Pritt (TWiP 75)

Reported cases of Lyme disease (CDC)

Signs and symptoms of Lyme disease (CDC)

Multilocus sequence typing

Borrelia MLST database

American Academy of Microbiology FAQ Human microbiome

Host fecal microRNA shapes gut microbiota (Cell)

Image credit

C.U.R.E. the game

Live Tiny, Die Never - Tardigrade T-shirt

This episode is sponsored by Microbe Magazine Podcast and ASM Microbe 2016

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

 



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TWiM #121: A plague of pathogens


Thu, Feb 11, 2016


Host: Vincent Racaniello

Special guests: Rebekah Kading and Wyndham Lathem

From the ASM Biodefense and Emerging Diseases Research meeting, Vincent speaks with Rebekah and Wyndham about their work on Rift Valley Fever virus and other vector-borne pathogens, and the evolution and pathogenesis of Yersinia pestis, the agent of plague.

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode 

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.



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TWiM #120: Snakes in trouble


Tue, Feb 02, 2016


Hosts: Vincent Racaniello and Elio Schaechter.

Vincent and Elio marvel in the finding that a phage tail-like structure from a marine bacterium stimulates tubeworm metamorphosis, and reveal Ophidiomyces as a cause of snake fungal disease.

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode 

This episode is sponsored by ASM Grant Writing Institute Online Webinar and 32nd Clinical Virology Symposium

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv.

 



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TWiM #119: Power of one


Sat, Jan 16, 2016


Hosts: Vincent RacanielloMichael Schmidt, and Elio Schaechter.

The microbophiles investigate the ratio of bacterial to human cells in our bodies, and how placing solar panels on a bacterium enables it to carry out photosynthesis.

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode 

This episode is sponsored by ASM Grant Writing Institute Online Webinar and 32nd Clinical Virology Symposium

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv.

Thumbnail image: Cell structure of a gram positive bacterium. This vector image is completely made by Ali Zifan - Own work; used information from Biology 10e Textbook (chapter 4, Pg: 63) by: Peter Raven, Kenneth Mason, Jonathan Losos, Susan Singer · McGraw-Hill Education.

 



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TWiM #118: Spore-drops keep fallin’ on my head


Fri, Jan 01, 2016


Hosts: Vincent Racaniello, Elio Schaechter and Michele Swanson

On the last episode for 2015, Vincent, Elio, and Michele discuss how soil amoeba hunt nematodes in packs, and the role of mushrooms as rainmakers.

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode 

This episode is sponsored by ASM Microbe 2016 and ASM Biodefense

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv.



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TWiM #117: Finding the comammox


Thu, Dec 17, 2015


The TWiM team marvels over the finding of a completely nitrifying Nitrospira, and horizontal gene transfer from Wolbachia into an animal genome.

Links for this episode:


This episode is sponsored by ASM Microbe 2016 and ASM Biodefense

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv.



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TWiM #116: Chewates and coconuts


Wed, Dec 02, 2015


Hosts: Vincent RacanielloElio Schaechter and Michele Swanson

The TWiMeriti reveal a Brazilian social bee that must cultivate a fungus to survive, and diet-mediated reduction in gut colonization by Candida albicans.

Links for this episode 

This episode is sponsored by ASM Biodefense and the 32nd Clinical Virology Symposium.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv.



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TWiM #115: Profiling the Poglianos


Fri, Nov 20, 2015


Vincent visits the laboratories of Kit and Joseph Pogliano on the campus of the University of California, San Diego, where he learns about their work on the bacterial cytoskeleton, sporulation, and the effects of antibiotics on bacterial cells.

Visit microbeworld.org/twim for complete shownotes including the special video version of this episode. Thanks for listening and watching!



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TWiM #114: Milestones in Blue


Fri, Nov 06, 2015


Vincent, Elio, and Michele meet with Harry Mobley, Mary O’Riordan, and Vince Young at the University of Michigan, during the designation of the Department of Microbiology and Immunology as a Milestones in Microbiology site. They discuss how the laboratory has advanced the science and teaching of microbiology, and discuss faculty work on uropathogenic E. coli, induction of stress by bacterial infection, and the gut microbiome.

Visit microbeworld.org/twim for more including the special video version of this episode.



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TWiM #113: Waves of Change


Thu, Oct 22, 2015


Vincent meets up with Romney and Duncan at the 79th annual meeting of the Southern California branch of the American Society for Microbiology, where they talk about emerging technologies for antimicrobial susceptibility testing, and next generation sequencing and advanced molecular diagnostics.

Visit microbeworld.org/twim to watch the video version and for complete shownotes including links mentioned.



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TWiM #112: Mushroom pickers and mushroom kickers


Sat, Sep 26, 2015


The TWiM team wonders why definitions in biology often change, and discuss how the small molecule terrein is important for the growth of a soil fungus.

Image: Lesion formation on banana surfaces infected with Aspergillus terreus. Source

Links mentioned:

 

Visit microbeworld.org/twim for more.

 



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TWiM #111: Ancientbiotics and modernbiotics


Thu, Sep 10, 2015


Hosts: Vincent RacanielloMichael Schmidt, and Elio Schaechter.

The TWiMitos discuss the reconstruction of a 1,000-year-old antimicrobial remedy, and using gallium as an antimicrobial in the battle for iron.

Subscribe to TWiM (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode 

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.



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TWiM #110: Exploring unseen life with unpronounceable words


Wed, Aug 19, 2015


The TWiM team focuses on the gut microbiome, from a single member, Akkermansia muciniphila, to the effect of antibiotics on its composition and colonization resistance against C. difficile.

Subscribe to TWiM (free) on iTunesStitcherAndroidRSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode 

Agar art contest

Akkermansia muciniphilia and obesity (Gut)

A. muciniphilia genome (Biol Direct)

Alterations of gut microbiota and C. difficile colonization (mBio)

Science Delivered

Girls Who Code

F.E.M.M.E.S.

Association for Women in Science

UMich Host-Microbiome Initiative

UMich anaerobic chamber room (png)



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TWiM #109: Precision killing


Thu, Aug 06, 2015


The TWiM cohort discusses the use of antimicrobial peptides to target specific bacteria in the microbiome, and how the intracellular bacterium Wolbachia selectively kills male hosts.

 

Links for this episode:

 

Image: Transmission electron micrograph of Wolbachia within an insect cell.

By: Scott O'Neill - Genome Sequence of the Intracellular Bacterium Wolbachia. PLoS Biol 2/3/2004: e76.



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TWiM #108: Vaccine in the time of cholera


Thu, Jul 23, 2015


Hosts: Vincent RacanielloMichael SchmidtElio Schaechter and Michele Swanson.  

The professors of TWiM discuss a University of Wisconsin plan for rescuing biomedical research in the US, and results of a clinical trial in Bangladesh of an oral cholera vaccine.

Subscribe to TWiM (free) on iTunesStitcherRSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode



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TWiM #107: The battle in your bladder


Thu, Jul 09, 2015


Hosts: Vincent Racaniello and Michael Schmidt.

Vincent and Michael discuss the highly diverse microbiome of uncontacted Amerindians, and how the composition of human urine plays a role in the battle for iron.

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.



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TWiM #106: Lawn mower disease


Wed, Jun 24, 2015


 

Vincent and Michael speak with Katy Bosio about her research on pathogenesis, immunity, and vaccines against Franciscella tularensis, the causative agent of tularemia.



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TWiM #105: Real bugs with legs


Fri, Jun 05, 2015


The TWiM team reviews the microbiological safety of herbs in the United Kingdom, and how a peptide from the milkweek bug binds the ribosome and inhibits bacterial protein synthesis.

 

Links for this episode:

 



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TWiM #104: Feed me polyamines, biofilm


Thu, May 21, 2015


Hosts: Vincent RacanielloMichael SchmidtElio Schaechter and Michele Swanson.  

The TWiM team discusses how measles vaccination protects against other infectious diseases, and links between bacterial biofilms and colon cancer.

Subscribe to TWiM (free) on iTunesStitcherRSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

Measles vaccination prevents all-cause infectious disease (Science)

Master of contagion (The Loom)

Video: Measles incidence to immunomodulation (Science)

FAQ: Adult vaccines

Metabolism links biofilms and colon cancer (Cell Metab)

Scripps Center for Metabolomics

Scripps metabolite database

Image credit

Sponsors for this episode: SciMedSolutionsICAAC-ICC

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

 



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TWiM #103: The battle for iron


Fri, May 08, 2015


Hosts: Vincent RacanielloMichael SchmidtElio Schaechter and Michele Swanson. 

The TWiM team is amazed by the ocelloid, and an evolutionary battle for iron between mammalian transferrin and bacterial transferrin-binding protein.

Subscribe to TWiM (free) on iTunesStitcherRSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

 



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TWiM #102: Happiness is the spore-formers in your gut


Fri, Apr 24, 2015


Hosts: Vincent RacanielloMichael SchmidtElio Schaechter and Michele Swanson. 

The TWiM team discusses evidence that serotonin synthesis is regulated by spore-forming members of the gut microbiota.

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Image: Serotonin temporary tattoo by flickr user: ChezShawna

 



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TWiM #101: The MRSA in your home


Wed, Apr 01, 2015


Hosts: Vincent RacanielloMichael SchmidtElio Schaechter and Michele Swanson. 

The TWiMers discuss how aroma helps disperse yeast cells on insect vectors, and evidence that MRSA is transmitted within households.

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

 



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TWiM #100: Omnis cellula e cellula


Wed, Mar 18, 2015


Hosts: Vincent RacanielloMichael SchmidtElio Schaechter and Jo Handelsman.  

The TWiM team celebrates 100 episodes with a Talmudic question, and discussion of how a single mutation alters bacterial host tropism.

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Image: Yellow colonies of S. aureus on a blood agar plate, note regions of clearing around colonies caused by lysis of red cells in the agar By: HansN. on wikimedia. From the study (Nat Gen) "...only a single naturally occurring nucleotide mutation was required and sufficient to convert a human-specific S. aureus strain into one that could infect rabbits." 



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TWiM #99: Careers in Biodefense


Wed, Mar 04, 2015


Hosts: Vincent Racaniello

Guests: Maria Julia MarinissenEdward H. You, and David R. Howell

Vincent meets up with Maria, Edward, and David at the ASM Biodefense and Emerging Infections Research meeting to talk about alternative careers for scientists.

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

 

A video version of this episode is available at microbeworld.org/twim 

Links for this episode:


Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.



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TWiM #98: Bacteria and eukaryotes get horizontal


Thu, Feb 19, 2015


 

The TWiM crew ponders the question of how a bacterium finds its middle when dividing, then divulge the transfer of interbacterial antagonism genes to eukaryotes, where they may function in innate defense.

 

Links for this episode:

 

Visit microbeworld.org/twim for complete shownotes and more.



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TWiM #97: There’s gold in them hills


Wed, Feb 04, 2015


The TWiM team reveal how bacteria in a shipworm’s gills help digest wood in the gut, and an approach that identifies a new antibiotic from the soil.

 

Links for this episode:

 

Visit microbeworld.org/twim for more.



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TWiM #96: A lean, mean sequencing machine


Wed, Jan 21, 2015


Hosts: Vincent Racaniello.

Special guest: Rob Knight

Vincent meets up with Rob Knight to talk about the technology that has fueled his drive to sequence the Earth and its inhabitants.

Check out the Microbeworld app.

Links for this episode

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.



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TWiM #95: A microbe lover in San Diego


Fri, Jan 09, 2015


Hosts: Vincent Racaniello.

Special guest: Stanley Maloy

Vincent meets up with Stan Maloy on the campus of San Diego State University to talk about his career in microbiology and his work as Dean of Science.

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode: 

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

 



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TWiM #94: Nitrochondria


Thu, Dec 25, 2014


Vincent, Elio, and Michael discuss a symbiosis between a nitrogen-fixing cyanobacteria and a single-celled eukaryotic alga.

 

Links for this episode:

 

Visit microbeworld.org/twim to view the complete shownotes and entire back catalog.



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TWiM #93: Worming in on bacteria


Thu, Dec 11, 2014


 

Vincent, Elio, and Michael reveal that a soil-dwelling nematode can recognize and respond to a bacterial quorum sensing molecule through a sensory neuron.



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TWiM #92: Flying biofilms


Thu, Nov 27, 2014


Vincent, Elio, Michael and Michele discuss the possible eradication of wild poliovirus type 3, and how microsporidian parasites prevent locust swarming behavior.

 



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TWiM #91: Rats, viruses, and bacteria


Fri, Nov 14, 2014


Vincent, Elio, and Michele review a study of the viruses and bacteria in commensal rats in New York City.

Visit microbeworld.org/twim for complete show notes. Thanks for listening!



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TWiM #90: Think globally, act locally


Wed, Oct 29, 2014


 

Vincent meets up with Laurene and David at the Annual Meeting of the Southern California Branch of the American Society for Microbiology, where they discuss how the Los Angeles County Department of Health is preparing for an outbreak of Ebola virus infection, and Cepheid’s game-changing, modular PCR system for the diagnosis of infectious diseases.



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TWiM #89: Microbial handoffs


Wed, Oct 15, 2014


Vincent, Michele, and Michael discuss how a gene from bacteria protects a tick from plant cyanide poisoning, and enhanced transmission of Streptococcus pneumoniae by influenza virus co-infection in mice.



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TWiM #88: A century of excellence in microbiology


Wed, Oct 01, 2014


Michele speaks with members of the Department of Bacteriology at the University of Wisconsin - Madison, on the occasion of its designation as a Milestones in Microbiology site, where they discuss how the department has advanced the science and teaching of microbiology.

 


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TWiM #87: Avogadro, archaeal fossils, and ICAAC


Wed, Sep 17, 2014


Vincent, Elio, and Michael explore the fossilization of archaeal lipids, and highlight the recent ICAAC in Washington, D.C.

 


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TWiM #86: Blurring the line between organelle and endosymbiont


Wed, Sep 03, 2014


Hosts: Vincent RacanielloMichael SchmidtElio Schaechter and Michele Swanson. 

Vincent, Elio, Michael, and Michele consider whether our eating behavior is manipulated by gastrointestinal microbiota, and an aphid gene of bacterial origin whose gene product encodes a protein that is transported to an obligate endosymbiont. 

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.



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TWiM #85: Oscillation in the ocean and a Verona integron


Thu, Aug 21, 2014


Vincent, Elio, Michael, and Michele discuss the diel transcriptional rythmns of bacterioplankton communities in the ocean, and extensively drug resistant Pseudomonas in Ohio.



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TWiM #84: Microbiology Down Under


Mon, Aug 11, 2014


In Melbourne, Australia Vincent speaks with David, Melanie, and Adam about their work on group A Streptococcus, Helicobacter pylori, and infections of Koalas with Chlamydia.



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TWiM #83: Illuminating tuberculosis and cryptococcosis


Thu, Jul 24, 2014


Vincent, Michael, Elio and Michele review a new fluorogenic diagnostic test for tuberculosis bacteria, and the role of a metalloprotease in helping a fungus invade the central nervous system. 

 


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TWiM #82: Betrayal and compromise


Thu, Jul 10, 2014


Hosts: Vincent RacanielloMichael SchmidtElio Schaechter and Michele Swanson.

Vincent, Michael, Elio and Michele discuss how an endosymbiont betrays its aphid host to alert plant defenses, and a new immunosuppressive cell that allows infection of neonates.

 

Subscribe to TWiM (free) on iTunes, via RSS feed, by email or listen on your mobile device with the Microbeworld app.

Links for this episode

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.



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TWiM #81: Cold iron is the master of them all


Sat, Jun 28, 2014


Vincent, Michael, and Michele discuss how iron might disperse bacterial biofilms in carotid arterial plaques, and controlling Salmonella by modulating host iron homeostasis. 



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TWiM #80: Hurling fleas and designer chromosomes


Wed, Jun 11, 2014


Hosts: Vincent RacanielloElio Schaechter, and Michele Swanson

Vincent, Elio, and Michele discuss how to synthesize a designer yeast chromosome, and deciphering the genetic changes path that allowed Yersinia pestis to be transmitted by fleas.

Links for this episode:

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.



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TWiM #79: A community of microbiologists


Thu, May 29, 2014


Vincent, Michael, and Michele review highlights of the 2014 General Meeting of the American Society for Microbiology in Boston, MA.



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TWiM #78: A bacterium grows in Brooklyn


Thu, May 15, 2014


Vincent, Elio, and Michael consider a fungal pathogen of insects that acquired a gene from its host that facilitates infection, and presence of gram-negative nosocomial pathogens on community surfaces near hospitals in Brooklyn. 



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TWiM #77: Zombie plants and no pain, no gain


Thu, May 01, 2014


Vincent, Elio, Michael, and Michelle review how a pathogen promotes plant attractiveness to insect vectors, and activation of sensory neurons that modulate pain and inflammation by bacterial infection.

 


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TWiM #76: Genetic biopixels and a pathogenic sweet tooth


Fri, Apr 11, 2014


Vincent, Elio, Michael, and Michelle discuss the use of bacteria to build a genetic sensor for heavy metals, and how host sugars help enteric pathogens to expand after antibiotic treatment.

 


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TWiM #75: Pellicles on pickle jars


Thu, Mar 27, 2014


Vincent, Elio, Michael, and Michelle discuss a symbiosis between a bacterium and fungus that increases the virulence of oral biofilms, and the assembly of amyloid fibers, which are needed for biofilm formation.

 


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TWiM #74: It came from the Siberian permafrost


Wed, Mar 12, 2014


Vincent, Elio, and Michael discuss a huge 30,000 year old virus recovered from Siberia, and nested symbiosis facilitated by horizontal gene transfer from bacteria to insect.



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TWiM #73: Eyeing root nodule development


Thu, Feb 27, 2014


Vincent, Michael, and Michele discuss how soil-dwelling bacteria induce the formation of root nodules on legumes via a protein called CYCLOPS. 



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TWiM #72: The benefits of virulence


Thu, Feb 13, 2014


Vincent, Elio, Michael, and Michele review how microbial virulence can be increased as a consequence of community surveillance and adaptation to macrophages.

 


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TWiM #71: Colon cancer’s little shop of horrors


Wed, Jan 22, 2014


Vincent, Michael, and Michele explain how the gut microbiome modulates colon tumorigenesis, and regulation of intestinal macrophage function by the microbial metabolite butyrate.



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TWiM #70: A paroxysmal cough


Wed, Dec 18, 2013


Vincent, Elio, Michael, and Michele discuss evidence that the acellular pertussis vaccine fails to prevent infection and transmission in nonhuman primates, and the use of bacterial cytological profiling to identify pathways targeted by antibiotics.



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TWiM #69: Bacterial DNA in the human genome


Wed, Nov 27, 2013


Vincent, Elio, Jo, and Michele review evidence for bacterial DNA integrated into the human genome, and control of the symbiont population in an insect midgut.




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TWiM #68: The fungus among us


Thu, Nov 14, 2013


Vincent, Elio, Michael, and Michele discuss the amazingly high level of intergenera gene exchange among haloarchaea in an Antarctic lake, and the diversity of fungi on residential surfaces and the human forehead. 



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TWiM #67: Black mushrooms and RNA thermosensors


Wed, Oct 30, 2013


Vincent, Elio, and Michael discuss how temperature triggers Neisseria menigitidis immune evasion, and protection of mice from ionizing radiation by feeding them black mushrooms.



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TWiM #66: The shape of a container


Thu, Oct 17, 2013


Vincent, Elio, Michael, and Michele discuss the curious outer membrane vesicles of Neisseria meningitides, and sources of Clostridium difficile infection revealed by genome sequencing.



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TWiM #65: Leanness is transmissible


Thu, Oct 03, 2013


Hosts: Vincent Racaniello and Michelle Swanson.

Vincent and Michelle reveal how the human gut microbiota can modulate obesity in mice.

Links for this episode: 

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.



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TWiM #64: URI and UTI at ICAAC in Denver


Wed, Sep 18, 2013


Vincent and Michael recorded this episode at the 53rd ICAAC in Denver, where they spoke with James Gern and James Johnson about rhinoviruses and extra-intestinal pathogenic E. coli.




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TWiM #63: Superantigens, S. aureus, and the armpit microbiome


Wed, Sep 04, 2013


Vincent, Michael, and Michelle discuss how a Staphylococcus aureus superantigen is critical for pathogenesis in a rabbit model, and the relationship of body odor to the axilla microbiome.



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TWiM #62: Breaking bad and protein chain mail


Wed, Aug 21, 2013


Vincent and Michael discuss how infection with influenza A virus disperses Streptococcus pneumoniae biofilms leading to disease, and an amazing protein chainmail in a viral capsid 



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TWiM #61: The irony of probiotics


Wed, Aug 07, 2013


Vincent, Elio, and Michele review how horizontal gene transfer from bacteria to an insect genome enables a tripartite nested mealybug symbiosis, and how probiotic bacteria work by competing for iron in the intestine.



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TWiM #60: Microbial electrochemistry and diversity-generating retroelements


Wed, Jul 24, 2013


Vincent, Elio, and Michael discuss how an error-prone reverse transcriptase produces enormous diversity in a Legionella protein, and using microbes to convert waste into bioelectricity and chemicals.



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TWiM #59: Are viruses part of our immune system?


Wed, Jul 10, 2013


Vincent and Michael discuss the finding that bacteriophage might be part of the mucosal antimicrobial defense system.



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TWiM #58: The brain microbiome?


Thu, Jun 20, 2013


Vincent, Elio and Michael review how underground mycelial networks carry signals that warn neighboring plants of aphid attack, and the presence of bacteria in the human brain.




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TWiM #57: Updating the human gut microbiome to degrade seaweed


Wed, Jun 05, 2013


Vincent, Elio and Michael discuss fungi that use pheromones to trap nematodes, and how genes obtained from marine bacteria help gut bacteria degrade algal carbohydrates. 



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TWiM #56: Live at ASM in Denver


Fri, May 24, 2013


Vincent, Elio and Michael recorded this episode before an audience at the 2013 General Meeting of the American Society for Microbiology in Denver, Colorado, where they spoke with Andrew, Ferric, Suzanne, and Michelle about their research on a phage system for evading innate immunity, retractions of research papers, bacterial infections of the eye, and cytoplasmic defenses against intracellular bacteria.

This episode was filmed live at ASM GM 2013 in Denver, CO. Visit www.microbeworld.org/asmlive to watch the full video archive of this episode as well as all the videos recorded during GM. 



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TWiM #55: In the copper room


Wed, Apr 24, 2013


Vincent, Elio and Michael discuss the finding that copper surfaces reduce microbial burden and hospital-acquired infections in the intensive care unit.



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TWiM #54: Dueling injectors and the microgenderome


Wed, Apr 10, 2013


Vincent, Elio, and Michael review how sex-dependent differences in the mouse microbiome regulate type I diabetes, and counterattack among bacteria.



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TWiM #53: Live in Manchester


Fri, Mar 29, 2013


Vincent, Laura, David, Kalin and Paul get together at the Society for General Microbiology meeting in Manchester, England to talk about next-generation approaches to antimicrobial therapy.



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TWiM #52: Clinical microbiology with Ellen Jo Baron


Mon, Mar 11, 2013


Vincent and Michael meet up with Ellen Jo Baron to talk about working in a clinical microbiology laboratory.


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TWiM #51: Cave science with Hazel Barton


Wed, Feb 27, 2013


Vincent, Michael, and Elio meet up with Hazel Barton to talk about cave microbiology.



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TWiM #50: These things aren’t even bacteria!


Wed, Jan 30, 2013


Vincent, Michael, and Stanley review the scientific career of Carl Woese.



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TWiM #49: Grape-like Clusters


Wed, Jan 16, 2013


Vincent, Michael, and Elio discuss the HIV co-receptor CCR5 as a receptor for S. aureus leukotoxin ED, and the vineyard yeast microbiome.




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TWiM #48: It’s all about direction


Thu, Jan 03, 2013


Vincent, Michael, and Jo discuss how subtle gender bias of science faculty favors male students, and the relationship of invasive infection and antibody orientation at bacterial surfaces.




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TWiM #47: Resistance on the surface


Wed, Dec 19, 2012


Horizontal transfer of antibiotic resistance genes on metal surfaces, and using bacteriophage to reverse antibiotic resistance.



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TWiM #46: Spore!


Wed, Dec 05, 2012


Vincent, Michael, and Elio meet up with Jonathan Dworkin to discuss how bacteria form spores and how they return to vegetative growth.



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TWiM #45: Secreted nucleic acids RIG a STING


Wed, Nov 21, 2012


Vincent, Michael, Elio review innate immune sensing of Listeria secreted bacterial nucleic acids, and how Wolbachia enhances egg production in Drosophila.



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TWiM #44: Phage interruptus


Wed, Oct 24, 2012


Vincent, Michael, Elio discuss the role of prophage excision in exit of Listeria from the phagosome, and analysis of bacterial communities in saliva.



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TWiM #43: Bacterial caveolae and zapping acne with phages


Wed, Oct 10, 2012


Vincent, Michael, Elio review formation of caveolae in a bacterium, and the limited genetic diversity and broad killing activity of P. acnes bacteriophages.



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TWiM #42: Staphylococcus, a three-star pathogen


Wed, Sep 26, 2012


Vincent, Michael, Elio, and Joe review highlights of the 15th International Symposium on Staphylococci and Staphylococcal Infections (ISSSI) in Lyon, France.



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TWiM #41: ICAAC live in San Francisco


Thu, Sep 13, 2012


Vincent and Michael travel to San Francisco for the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), where they meet with Bill, John, and Victor to discuss tuberculosis, monitoring infectious disease outbreaks with online data, and outside-the-box approaches to antibacterial therapy.




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TWiM #40: A mecca for microbiology


Wed, Aug 29, 2012


**MicrobeWorld app users, click the "e" symbol in the bottom right corner of this description to watch a bonus video version of this episode!**

Vincent and Stanley meet with Waclaw Szybalski and John Kirby at Cold Spring Harbor Laboratory on the occasion of its designation as a Milestones in Microbiology site. They reminisce about how the well known laboratory has advanced the science and teaching of microbiology, and discuss John’s work on the soil dwelling, predatory myxobacteria.

If you don't have the app, please visit www.microbeworld.org/app to get more information about downloading the app for your iOS or Android device.

This video is also available for free at www.microbeworld.org in the TWiM section, epsiode #40.




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TWiM #39: What Darwin never knew


Wed, Aug 15, 2012


Vincent, Michael, and Elio reviews chapters from Microbes and Evolution, a collection of short, personal essays by microbiologists.




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TWiM #38: The sound of whooping cough


Thu, Aug 02, 2012


Vincent, Jo, Michael, and Elio review an outbreak of pertussis in Washington, and how culturing can reveal rare members of the soil biosphere.



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TWiM #37: Microbial Jekyll and Hyde


Wed, Jul 18, 2012


Vincent, Jo, Michael, and Elio discuss two examples of dynamic microbial symbioses that switch between mutualistic and pathogenic states.



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TWiM #36: Domesticating a pathogen


Wed, Jul 04, 2012


Vincent, Michael, and Elio explore the origin of Mycoplasma pathogens of ruminants, and share their thoughts on the recent ASM General Meeting.



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TWiM #35: Ohne hauch


Thu, Jun 21, 2012


Vincent, Michael, and Elio review necrotizing fasciitis, and a link between surface remodeling in gram-positive and gram-negative bacteria.



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TWiM #34: Doing the DISCO with Emiliania


Mon, Jun 04, 2012


Hosts: Vincent RacanielloMichael Schmidtand Elio Schaechter

Vincent, Michael, and Elio discuss changing populations of Emiliania huxleyi and their viruses in the North and Black Seas.

Right click to download TWiM #34 (50 MB .mp3, 69 minutes).

Links for this episode:



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TWiM #33: Tuning the immune organ


Wed, May 16, 2012


Vincent, Michael, and Ivo review the requirement for segmented, filamentous bacteria for the induction of a specific type of helper T cell in the gut.

Links for this episode:

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv , 



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TWiM #32: Not the shadow biosphere


Wed, May 02, 2012


Rosie Redfield talks about her evidence that a bacterium cannot grow on arsenic instead of phosphorus. 



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TWiM 31: Screen door on a submarine


Wed, Apr 18, 2012


Hosts: Vincent RacanielloJo Handelsmanand Michael Schmidt

Vincent, Jo, and Michael discuss an archetypal protein transport system in bacterial outer membranes, and evidence that gut microbial enterotypes might not fall into defined groups.

Links for this episode:



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TWiM #30: Unraveling melioidosis and insulin resistance


Wed, Apr 04, 2012


On episode #30 of the podcast, Vincent, Elio, and Michael review how a toxin from Burkholderia pseudomallei inhibits protein synthesis, and the role of the gut microbiome in modulating insulin resistance in mice lacking an innate immune sensor.



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TWiM #29: Death and an iron-loaded spike


Wed, Mar 21, 2012


On episode #29 of the podcast, Vincent and Stanley review how a phage pierces the cell membrane with an iron-loaded spike, and two programmed cell death systems in E. coli.



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TWiM #28: Not unorganized bags of enzymes


Wed, Mar 07, 2012


Vincent, Michael, and Elio review how competition within a host drives virulence of Streptococcus pneumoniae, and the expanding universe of the bacterial cytoskeleton.



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TWiM #27: An inflamed gut is good for Salmonella


Wed, Feb 22, 2012


Vincent, Elio, and Michael review how inflammation allows Salmonella to compete with fermenting gut microbes, and a riboswitch in bacterial and Archeal species that is triggered by fluoride.



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TWiM #26: Suum cuique


Wed, Feb 08, 2012


Vincent, Elio, and Michael discuss the finding of Sutterella species in the gut of autistic children, and methods for cultivating oral bacteria. 



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TWiM #25: Magnetotactic bacteria and totally drug resistant TB


Wed, Jan 25, 2012


On episode #25 of the podcast, Vincent, Elio, and Michael review bacteria that use the earth’s magnetic field for navigation, and identification of totally drug resistant Mycobacterium tuberculosis.



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TWiM #24: This year in microbiology


Wed, Jan 11, 2012


Vincent, Michael, and Cliff review ten compelling microbiology stories from 2011.



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TWiM #23: Fighting antibiotics with toxic gas and starvation


Wed, Dec 28, 2011


Vincent, Jo, Elio, and Michael explain how a swarming bacterium helps disperse a non-motile fungus, and bacterial antibiotic tolerance mediated by hydrogen sulfide and starvation responses.



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TWiM #22: Microbiology 911


Wed, Dec 14, 2011


Vincent and Michael speak with Alfred Sacchetti, MD, Chief of Emergency Services at Our Lady of Lourdes Medical Center, about microbial infections encountered in the emergency room.



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TWiM #21: Symbiotic margheritas


Wed, Nov 30, 2011


Vincent and Elio discuss ancient symbiosis between Alphaproteobacteria and catenulid flatworms, and a toxin from Helicobacter pylori that engages the mitochondrial fission machinery to induce host cell death.



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TWiM #20: Facebook for bacteria


Wed, Nov 16, 2011


On episode #20 of the podcast This Week in MicrobiologyVincent, Michael, and Elio follow up on the outbreaks of E. coli in Germany and cholera in Haiti, then discuss genes that confer self-identity to Proteus mirabilis.



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TWiM #19: Your microbiome is what you eat


Wed, Nov 02, 2011


Vincent, Michael, Elio, and Jo discuss the genome sequence of Y. pestis from victims of the Black Death, and the effect of diet on gut microbial enterotypes.



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TWiM #18: Escherichia coli K-12, an emerging pathogen?


Wed, Oct 19, 2011


Vincent, Michael, Elio, and Stanley explain how to make the human intestinal commensal and benign laboratory bacterium Escherichia coli K-12 into an invasive organism, and the unearthing of century-old spores in New York City.



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TWiM #17: Debugging endosymbiosis


Wed, Oct 05, 2011


Vincent, Michael, and Elio focus on endosymbiosis: the rapid spread of Ricekttsia in whitefiles, and a metabolic patchwork in nested symbionts of mealybugs.



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TWiM #16: ICAAC Live


Thu, Sep 22, 2011


On episode #16 of the podcast This Week in MicrobiologyVincentMichaelArturoStuart, and David converse about antimicrobial resistance and why most fungi do not cause disease at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).



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TWiM #15: Microbial long distance relationships


Wed, Sep 07, 2011


On episode #15 of the podcast This Week in Microbiology, Vincent, Michael and Jo review the number of species on Earth, evidence that the 2010 Haitian cholera outbreak originated in Nepal, and how gut microbiota influence the immune response to influenza virus infection of the lung. 



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TWiM #14: Vomocytosis and microbial transistors


Wed, Aug 24, 2011


On episode #14 of the podcast This Week in MicrobiologyStanley, Margaret, Michael and Elio review how the fungus Cryptococcus escapes from macrophages, and electrical conductivity in nanowires formed by the bacterium Geobacter.



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TWiM #13: Probiotics and inflammasomes: Telling good bacteria from the bad


Wed, Aug 10, 2011


On episode #13 of the podcast This Week in Microbiology, Stanley, Jo, Michael and Elio discuss how colonic microbial ecology and risk for colitis are regulated by an inflammasome, and amelioration of intestinal inflammation in mice by delivery of a probiotic-derived soluble protein to the colon.



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TWiM #12: Photothermal nanoblades and genome engineering


Wed, Jul 27, 2011


Vincent, Margaret, Michael and Elio review the use of photothermal nanoblades to dissect the Burkholderia intracellular life cycle, and manipulation of chromosomes in vivo for genome-wide codon replacement in E. coli.



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TWiM #11: Chickens, antibiotics, and asthma


Wed, Jul 13, 2011


Vincent, Margaret, Michael and Elio review the presence of extended spectrum beta-lactamase genes in chicken meat and in humans, and a beneficial effect of Helicobacter pylori colonization on the development of allergen-induced asthma.



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TWiM #10: A symbiotic cloaking device


Wed, Jun 29, 2011


On episode #10 of the podcast This Week in Microbiology, Vincent, Margaret, Elio, Michael and Dickson discuss the symbiosis between the Hawaiian bobtail squid and the luminous, gram-negative bacterium Vibrio fischeri.



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TWiM #9: Bean sprouts and E. coli O104:H4


Wed, Jun 15, 2011


Vincent, Michael, and Cliff review the outbreak of bloody diarrhea and hemolytic uremic syndrome in Germany caused by Shiga toxin-producing Escherichia coli O104:H4.



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TWiM # 8: Live in NOLA


Wed, Jun 01, 2011


Vincent, Michael, and Stanley recorded TWiM #8 live at the 2011 ASM General Meeting in New Orleans, with guests Andreas Ba?mler, Nicole Dubilier, and Paul Rainey. They spoke about how pathogens benefit from disease, symbioses between chemosynthetic bacteria and marine invertebrates, and repetitive sequences in bacteria.



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TWiM #7: Cycles of life and death, light and dark


Wed, May 18, 2011


Vincent, Cliff, Elio, Margaret, and Michael discuss programmed cell death in E. coli, and the daily synthesis and degradation of enzymes needed for photosynthesis and nitrogen fixation by cyanobacteria.



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TWiM #6: Antibacterial therapy with bacteriophage: Reality or fiction?


Wed, May 04, 2011


Vincent, Cliff, Michael and Elio review the use of bacteriophages to manage infections, and the presence of antibiotic resistance genes in the bacteriophage from urban sewage and river water.



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TWiM #5: Mercury-methylating Desulfovibrio and antimicrobial nanoparticles


Wed, Apr 20, 2011


Vincent, Ron, Cliff, and Michael discuss the genome sequence of a mercury-methylating bacterium and the antimicrobial effects of nanoparticles.



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TWiM #4: Cantaloupes and Salmonella gastroenteritis


Wed, Apr 06, 2011


Vincent, Cliff, Margaret, and Michael review foodborne bacterial illness in the context of outbreaks associated with cantaloupes and Lebanon bologna.



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TWiM #3: Anthrax, genomics and the FBI inquiry


Wed, Mar 23, 2011


Vincent, Jo, Cliff, and Ron explore the genome analysis done in support of the Amerithrax investigation, and an insecticidal enterotoxin-deficient mutant of Bacillus thurigiensis.



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TWiM #2: The plague, microbial virulence and the gut microbiome


Wed, Mar 09, 2011


Vincent, Cliff, and Michael review a fatal laboratory acquired Yersinia pestis infection, and how gut bacteria control body weight and metabolic activity.



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TWiM #1: Neisseria LINEs up


Wed, Feb 23, 2011


On episode #1 of the podcast This Week in Microbiology, Vincent, Cliff, Michael, and Stan discuss transfer of DNA from a human host to a bacterial pathogen, and the ability of dry copper to kill bacteria on contact.



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